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Ampicillin

Ampicillin

Ampicillin

250mg 270pills
$0.24 per pill Order

Select Doses:250mg500mg

250mg
90pills
Ampicillin $40.00
$32.99
$0.37 per pill
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save:$0.00
250mg
120pills
Ampicillin $42.00
$34.99
$0.29 per pill
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save:$9.60
250mg
180pills
Ampicillin $58.00
$47.99
$0.27 per pill
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save:$18.00
250mg
270pills
Ampicillin $77.00
$63.99
$0.24 per pill
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save:$35.10
500mg
10pills
Ampicillin $18.00
$14.99
$1.50 per pill
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save:$0.00
500mg
20pills
Ampicillin $29.00
$23.99
$1.20 per pill
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save:$6.00
500mg
30pills
Ampicillin $38.00
$31.99
$1.07 per pill
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save:$12.90
500mg
60pills
Ampicillin $70.00
$57.99
$0.97 per pill
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save:$31.80
500mg
90pills
Ampicillin $95.00
$78.99
$0.88 per pill
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save:$55.80
500mg
120pills
Ampicillin $113.00
$93.99
$0.78 per pill
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save:$86.40
500mg
180pills
Ampicillin $154.00
$127.99
$0.71 per pill
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save:$142.20
500mg
270pills
Ampicillin $206.00
$171.99
$0.64 per pill
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save:$232.20
Ampicillin is a broad-spectrum antibacterial bactericidal agent from the group of semisynthetic penicillins. It is obtained by acetylation of 6-aminopenicillanic acid with an aminophenylacetic acid residue. It is acid-resistant. This antibiotic inhibits peptidoglycan polymerase and transpeptidase. It prevents the formation of peptide bonds and disrupts the late stages of the synthesis of dividing microorganism’s cell walls. It results in a decrease in the osmotic resistance of the bacterial cell and causes its lysis.

Ampicillin is active against gram-positive (alpha and beta-hemolytic streptococci, Streptococcus pneumoniae, Staphylococcus spp., Bacillus anthracis, Clostridium spp., Most enterococci, including Enterococcus faecalis, and Neem-negative (Haemophiliss prussitrie merizaidae meninga, influenza Pasteurella multocida many species of Salmonella spp., Shigella spp., Escherichia coli) microorganisms, aerobic non-spore forming bacteria (Listeria spp.).

Indications

Bacterial infections caused by sensitive microflora:

  • respiratory tract and ENT organs (sinusitis, tonsillitis, pharyngitis, otitis media, bronchitis, pneumonia, lung abscess);
  • kidney and urinary tract infections (pyelonephritis, pyelitis, cystitis, urethritis;
  • infections of the biliary system ( cholangitis, cholecystitis), gonorrhea, chlamydial infections in pregnant women (with erythromycin intolerance);
  • cervicitis, infections of the skin and soft tissues: erysipelas, impetigo, secondarily infected dermatoses;
  • musculoskeletal infections;
  • pasteurellosis;
  • listeriosis;
  • infections of the gastrointestinal tract (typhoid and paratyphoid fever, dysentery, salmonellosis, salmonella carriage, peritonitis).
Oral administration. The dosage regimen of Ampicillin in adults is 0.25 g 4 times a day for 0.5-1 hours before meals with a small amount of water. If necessary, increase the dose to 3 g/day.

Infections of the gastrointestinal tract and organs of the genitourinary system: 0.5 g 4 times a day.

Gonococcal urethritis – 3.5 g once.

A mild infection in children, it is preferable to use a suspension.

Children over 4 years old are prescribed 1-2 g per day. The daily dose is divided into 4-6 doses.

The duration of therapy depends on the condition severity (from 5-10 days to 2-3 weeks, in chronic processes – for several months).

The most common contraindications of Ampicillin are:

  • hypersensitivity (including to other penicillins, cephalosporins, carbapenems);
  • infectious mononucleosis;
  • lymphocytic leukemia;
  • liver failure;
  • a history of gastrointestinal tract diseases (especially colitis associated with the use of antibiotics);
  • lactation;
  • children (up to 4 years).

Take this antibiotic with caution in the following cases:

  • bronchial asthma;
  • hay fever;
  • allergic diseases;
  • renal failure;
  • a history of bleeding;
  • pregnancy.
  • Allergic reactions: possible – skin peeling, itching, urticaria, rhinitis, conjunctivitis, Quincke’s edema; rarely – fever, arthralgia, eosinophilia, erythematous and maculopapular rash, exfoliative dermatitis, erythema multiforme, including Stevens-Johnson syndrome, reactions similar to serum sickness, in isolated cases – anaphylactic shock.
  • Digestive system: dysbiosis, stomatitis, gastritis, dry mouth, taste change, abdominal pain, vomiting, nausea, diarrhea, stomatitis, glossitis, impaired liver function, a moderate increase in hepatic transaminases, pseudomembranous enterocolitis.
  • Central nervous system: agitation or aggressiveness, anxiety, confusion, behavior change, depression, convulsions (with high-dose therapy).
  • Laboratory indicators: leukopenia, neutropenia, thrombocytopenia, agranulocytosis, anemia.
  • Other: interstitial nephritis, nephropathy, superinfection (especially in patients with chronic diseases or reduced body resistance), vaginal candidiasis.
  • Antacids, glucosamine, laxatives, food slow down and reduce absorption; ascorbic acid increases absorption.
  • Bactericidal antibiotics (including aminoglycosides, cephalosporins, cycloserine, vancomycin, rifampicin) – synergistic effect; bacteriostatic drugs (macrolides, chloramphenicol, lincosamides, tetracyclines, sulfonamides) – antagonistic.
  • Ampicillin increases the effectiveness of indirect anticoagulants (suppressing the intestinal microflora, reduces the synthesis of vitamin K and the prothrombin index).
  • It reduces the effectiveness of estrogen-containing oral contraceptives (additional contraceptive methods must be used), drugs that metabolize para-amino-benzoic acid, ethinyl estradiol.
  • Diuretics, allopurinol, oxyphenbutazone, phenylbutazone, non-steroidal anti-inflammatory drugs; drugs that block tubular secretion increase the concentration (due to a decrease in tubular secretion).
  • Allopurinol increases the risk of developing a skin rash.
  • Ampicillin reduces clearance and increases the toxicity of methotrexate and enhances digoxin absorption.
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